Disclosed herein are a method and a system for creating a registered image that integrates the information of CT and CBCT images. With the present method and system, medical practitioners can precisely transform the information of CT image-based treatment plan into the CBCT image so as to accurately control the dosage and location of a radiation therapy. Accordingly, also disclosed herein are methods of treating a cancer in the subject with the aid of the method and/or system of the present disclosure.本揭示內容是關於用以產生對位影像的方法及系統,其中該對位影像整合了CT及CBCT影像的資訊。醫療人員可利用本揭示內容之方法及系統,將歸劃於CT影像之治療計畫的資訊精確轉換為CBCT影像,藉以準確調控放射治療的劑量及位置。據此,本揭示內容亦提供利用本發明方法及/或系統來治療個體之癌症的方法。