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Azabicyclic compound or salt thereof
专利权人:
大鵬薬品工業株式会社
发明人:
北出 誠,大久保 秀一,吉村 千穂子,山下 智史,鴛海 宏美,宇野 貴夫,河合 祐一
申请号:
JP2011521828
公开号:
JP5227456B2
申请日:
2010.07.09
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
It is intended to provide a novel azabicyclo compound which exhibits both HSP90 inhibitory activity and cell proliferation inhibitory effect. Specifically disclosed is a compound represented by the following general formula (I) or a salt thereof: wherein X 1 represents CH or N; any one of X 2 , X 3 and X 4 represents N, and the others represent CH; any one or two of Y 1 , Y 2 , Y 3 and Y 4 represent C-R 4 , and the others are the same or different and represent CH or N; R 1 represents an optionally substituted monocyclic or bicyclic unsaturated heterocyclic group having 1 to 4 heteroatoms selected from N, S and O; R 2 represents an alkyl group having 1 to 6 carbon atoms, or the like; and R 3 and R 4 represent -CO-R 5 or the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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