MODULATION DE L'ACTIVITÉ DE PRO-NEUROTROPHINES

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专利权人:

H. Lundbeck A/S

发明人:

申请号：

EP07846437.7

公开号：

EP2120997B1

申请日:

2007.12.21

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present invention provides agents for inhibiting binding of a pro-neurotrophin to a Vps10p-domain receptor, in particular the binding of a pro-NGF or a pro-BDNF to a Sortilin receptor. The invention thus provides agents for the manufacture of a medicament, for treating and/or preventing disease or disorders such as but not limited to neurological, neuropsychiatric and ocular diseases, disorders, and degeneration as well as obesity, diabetes, pain and/or nociception in an individual.

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