FISCHER, Nicolas,MAGISTRELLI, Giovanni,MASTERNAK, Krzysztof
申请号：
AU2018303254
公开号：
AU2018303254A1
申请日:
2018.07.23
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
The invention relates to the generation of multispecific antibody mixtures include a subset of antibodies isolated from a mixture of two or more monospecific antibodies and one or more bispecific antibodies, wherein all antibodies in the subset have the same common heavy chain. The invention also relates to methods of isolating, purifying, or otherwise producing such a subset of antibodies by using at least one afÍinity chromatography step. The invention also relates to methods of using such a subset of antibodies in a variety of therapeutic indications.
