Elin Marianne Monie,Tomas Bjorkman,Anna Gronberg,Anders Ljunglof,Gustav Jose Rodrigo,Karin Torstenson,Magnus Carl Erik Wetterhall
申请号：
US15554075
公开号：
US20180036445A1
申请日:
2016.02.25
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention discloses a method for cleaning or sanitization of an affinity chromatography matrix, comprising the steps of: a) providing an affinity chromatography matrix having oxidation-tolerant proteinaceous ligands coupled to a support, b) contacting the matrix with a sanitization solution comprising at least one oxidant defined by formula I, R—O—O—H (I) wherein R is hydrogen or an acyl group R′—C(O)—, with R′ being a hydrogen or a methyl, ethyl or propyl group.
