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Pharmaceutical Compositions of Edoxaban
专利权人:
Sandoz AG
发明人:
Johannes Raneburger,Hossam Farouk
申请号:
US15501518
公开号:
US20170231969A1
申请日:
2015.05.13
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Edoxaban is factor X inhibitor useful for the treatment or the prevention of thrombosis or embolism. A pharmaceutical composition comprising Edoxaban, or a pharmaceutically acceptable salt thereof, a water soluble vinylpyrrolidone polymer selected from the group consisting of povidone and copovidone, and a cellulose ether, and not comprising a sugar alcohol, having good dissolution and bioavailability is provided. A process for its preparation, a dosage form comprising such composition, and the use of said pharmaceutical composition and dosage form as a medicament are also disclosed.
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