A problem to be solved by the present invention is the provision of an ophthalmic pharmaceutical composition with enhanced preservative effectiveness and/or improved light stability of carteolol. The problem may be solved by combining carteolol or a pharmaceutically acceptable salt thereof with edetic acid or a pharmaceutically acceptable salt thereof.本發明所解決的問題為提供具有卡替洛爾的增強防腐有效性及/或改善的光穩定性的眼科藥用組成物。該問題可藉由組合卡替洛爾或其醫藥可接受鹽與依地酸或其醫藥可接受鹽而予以解決。