COMPOSITIONS À BASE DE VECTEURS RAAV COMPRENANT DES PROTÉINES DE CAPSIDE MODIFIÉES PAR LA TYROSINE ET PROCÉDÉS D'UTILISATION CORRESPONDANTS

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专利权人:

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION; INC.

发明人:

申请号：

EP08733161.7

公开号：

EP2191001B1

申请日:

2008.04.08

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant rAAV vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene therapy, and large-scale production of rAAV vectors.

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中国工程科技知识中心

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