INC.;PANACELA LABS, INC.;ROSWELL PARK CANCER INSTITUTE;PANACELA LABS
发明人:
GUDKOV, ANDREI, V.
申请号：
EP10822611
公开号：
EP2486134A4
申请日:
2010.10.06
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The present invention is directed to methods and agents used for treating cancer or infectious diseases by providing toll-like receptors such as toll-like receptor 5 (TLR-5) in combination with providing a toll-like receptor agonists such as flagellin resulting in a cis and in-trans effect that recruits cells involved in both the innate (cis effect) and adaptive (trans effect) immune response to specifically kill cancer cells and cells infected with a pathogen via the NF-&kgr；B apoptosis pathway.
