John A. Chiorini,Sandra Wainer,Mavis Agbandje-McKenna,Sujata Halder
申请号：
US15092482
公开号：
US20160289275A1
申请日:
2016.04.06
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A modified adeno-associated virus (AAV) capsid protein comprising at least one non-native amino acid that confers to the modified AAV particles new properties, such as increased transduction efficiency and reduced immunogenicity. These modified AAV proteins and particles are particularly useful for gene therapy and the treatment of various diseases and conditions.
