The present invention relates to the method and device for production of coating with antimicrobial properties, namely the method of production of polypropylene film coated with thin layer of oxidized graphene, where by this method coated polypropylene films can be used in food industry, medicine. Method for the production of the coating with antimicrobial properties includes the coating of polypropylene film with the thin layer of graphene. Having aim to simplify the covering protocol and equipment thereof, graphite powder is evenly distributed on the surface of polypropylene film by means of mechanical covering and forming of the thin layer of graphene, such way prepared polypropylene film is washed with water and graphene layer is oxidized. After oxidation a polypropylene film with thin layer of graphene oxide is washed with water and dried.