KEIL, STEFANIE,BERNARDELLI, PATRICK,URMANN, MATTHIAS,MATTER, HANS,WENDLER, WOLFGANG,GLIEN, MAIKE,CHANDROSS, KAREN,LEE, LAN
申请号:
PL06792252
公开号:
PL1931660T3
申请日:
2006.09.26
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
The present invention comprises phenyl-[1,2,4]-oxadiazol-5-one derivatives of the general formula I: wherein the R1-R10 and B, U, V, W, X, Y and Z substituents are defined herein. The claimed invention also comprises the compounds isomers and their physiologically acceptable salts as well as processes for their preparation. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.