A biopsy device is provided. The biopsy device comprises a body and a needle extending distally relative to the body, wherein the needle defines a first lumen and a second lumen, wherein the first lumen extends along a first longitudinal axis, wherein the second lumen extends along a second longitudinal axis, wherein the needle includes an opening fluidly coupling the first lumen with the second lumen. The biopsy device further comprises a cutter, wherein the cutter is configured to translate relative to the needle to sever tissue, and a valve assembly, the valve assembly including a vent opening, and a spool body including a plurality of vent channels extending through at least a portion of the spool body such that the plurality of vent channels are configured to communicate fluid from a proximal end portion of the spool body to a distal end portion of the spool body, wherein the spool body is movable relative to the vent opening between a first position and a second position, wherein the valve assembly is configured to couple the second lumen of the needle to the vent opening via at least one vent channel of the plurality of vent channels when the spool body is in the first position, wherein the valve assembly is configured such that the second lumen is sealed relative to the vent opening when the spool body is in the second position.
