Daniel Aicher,Arno Wiehe,Christian B. W. Stark,Volker Albrecht,Susanna Gräfe
申请号:
US13208917
公开号:
US09156849B2
申请日:
2011.08.12
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides biologically active compounds that can be used as photosensitizers for diagnostic and therapeutic applications, particularly for PDT of cancer, infections and other hyperproliferative diseases, fluorescence diagnosis and PdT treatment of a non-tumorous indication such as arthritis, inflammatory diseases, viral or bacterial infections, dermatological, ophthalmological or urological disorders. The compounds are of the class of β-functionalized hydroxy- and dihydroxy-chlorins having the general formula