PROBLEM TO BE SOLVED: To provide a pharmaceutical composition or kit comprising a diindolylmethane compound for treating a skin condition, such as acne.SOLUTION: A composition for a skin condition comprises: (a) a first component comprising a substituted or unsubstituted diindolylmethane compound； and (b) a second component comprising a retinoid compound (a vitamin A compound, particularly vitamin A palmitate). Preferably, the composition further comprises a substituted/unsubstituted retinoid compound or the like as a third component.EFFECT: The combination with the second component exhibits significant synergistic effect on acne, inflammation and skin aging.SELECTED DRAWING: None【課題】にきび等の皮膚症状の治療のためのジインドリルメタン化合物を含む医薬組成物又はキットの提供。【解決手段】皮膚症状のための組成物であって、（ａ）置換又は無置換のジインドリルメタン化合物を含む第１の成分と、（ｂ）レチノイド化合物（ビタミンＡ化合物、特にビタミンＡパルミチン酸塩）を含む第２の成分とを含有する組成物。好ましくは、第３の成分として置換／無置換のレチノイド化合物等を更に含む組成物。【効果】第２の成分と組み合わせることにより、にきび、炎症、皮膚老化に相乗的な顕著な効果を発現。【選択図】なし
