A Desmodium styracifolium (Osb.) Merr. flavonoids capsule, a method of preparing same, and use thereof. The Desmodium styracifolium (Osb.) Merr. flavonoids capsule comprises: Desmodium styracifolium (Osb.) Merr. flavonoids, being alcohol extract of Desmodium styracifolium (Osb.) Merr.; and a pharmaceutically acceptable excipient. The capsule is used for treating urinary tract calculi.