Shanghai Hengrui Pharmaceutical Co., Ltd.;Jiangsu Hengrui Medicine Co., Ltd.
发明人:
Dong LIU,Biao LU,Wenjian QIAN,Huaide DONG,Suxing LIU,Rumin ZHANG,Feng HE,Weikang TAO
申请号:
US16627590
公开号:
US20200131123A1
申请日:
2018.07.05
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A solid dispersion, a method for preparing same, and a solid preparation comprising the solid dispersion. The solid dispersion contains (R)-4-amino-1-(1-(but-2-ynylacyl)pyrrolidin-3-yl)-3-(4-(2,6-difluorophenoxy)phenyl)-1,6-dihydro-7H-pyrrolo[2,3-d]pyridazine-7-one or a pharmaceutically acceptable salt thereof, and a carrier material. The carrier material is selected from hydroxypropyl methylcellulose acetate succinate and hydroxypropyl methylcellulose phthalate.