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TUMOR ANTIGEN PEPTIDE
专利权人:
发明人:
TORIGOE, TOSHIHIKO,鸟越俊彦,鳥越俊彥,ATSUYAMA, ERI,厚山惠里,厚山惠里,OTAKA, HIRONORI,大鹰弘纪,大鷹弘紀,NAKANO, KAZUE,中野一绘,中野一繪,LI, DONGLIANG,李栋梁,李棟梁,TOJI, SHINGO,田路真悟,田路真悟,ASANO, TAKUYA,浅野拓也,淺野拓也,HORIBE, RYOTA,堀部亮多,堀部亮多,HIRO
申请号:
TW104131694
公开号:
TW201625663A
申请日:
2015.09.24
申请国别(地区):
TW
年份:
2016
代理人:
摘要:
The invention is directed to providing a tumor antigen peptide which is specifically expressed in a cancer cell and a cancer stem cell, and to providing a pharmaceutical composition containing such a tumor antigen peptide as an effective ingredient, wherein the tumor antigen peptide is beneficial for preventing and/or treating a cancer.For the aforementioned purpose, the problems are addressed in the invention by providing the follows: a partial peptide derived from BORIS (Brother of Regulator of Imprinted Sites) belonging to isoform A or C or belonging to isoform subgroup 5 or 6 a polynucleotide encoding the aforementioned peptide a pharmaceutical composition containing said peptide and/or polynucleotide as the effective ingredient and a cancer prophylactic and/or therapeutic agent which is characterized in that the agent can induce cytotoxic T cells.本發明之目的在於提供一種腫瘤抗原胜肽,其特異性地被呈現在癌及癌幹細胞;及,提供一種含有此腫瘤抗原胜肽來作為有效成分之醫藥組成物等,其有益於癌的預防及/或治療。為了達成上述目的,本發明是藉由提供下述來解決問題:一種部分胜肽,其源自屬於同型異構物A或C、或者是亞型5或6的BORIS(印記位點調節物兄弟);一種聚核苷酸,其編碼出前述胜肽;一種醫藥組成物,其含有該等胜肽及/或聚核苷酸來作為有效成分;及,一種癌的預防及/或治療劑等,其特徵在於會誘導出細胞毒性T細胞。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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