The present utility model relates to the field of medical instruments, and provides a collimating body and a multi-source focusing radiation therapy head, which may adjust the shape of an irradiation field of a focal point, as well as radiation dosage. The collimating body comprises: a first collimating portion and a second collimating portion, the first collimating portion and the second collimating portion being arranged side by side and being closely attached; the first collimating portion is provided thereon with a first collimating hole set, and the second collimating portion is provided thereon with a second collimating hole set; the first collimating portion and the second collimating portion may be oppositely moved in a direction perpendicular to the side by side arrangement so as to align or stagger the first collimating hole set and the second collimating hole set.