THE UNIVERSITY OF BRITISH COLUMBIA;BRITISH COLUMBIA CANCER AGENCY BRANCH
发明人:
YAN, LUPING,ANDERSEN, RAYMOND J.,SADAR, MARIANNE DOROTHY,MAWJI, NASRIN R.,BANUELOS, CARMEN ADRIANA
申请号:
CA2948643
公开号:
CA2948643A1
申请日:
2015.05.29
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Compounds having a structure of Structure I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R4, R6, Y1 and Y2 are as defined herein, and wherein at least one of R3 or R4 is a straight-chain C1-C6 haloalkyl, are provided. Uses of such compounds for treatment of various indications, including prostate cancer, as well as methods of treatment involving such compounds are also provided.