第13型17β羥基類固醇脫氫酶(HSD17B13)iRNA組成物及其使用方法农业专利-农业专业知识服务系统

发明人:: HINKLE, GREGORY,辛克尔　格雷戈里,辛克爾　格雷戈里,TREMBLAY, FREDERIC,特伦布莱　弗雷德里克,特倫布萊　弗雷德里克,ABUL-HUSN, NOURA S.,阿布胡森　努拉Ｓ,GOTTESMAN, OMRI,戈特斯曼　暗利,LI, ALEXANDER,李　亚历山大,李　亞歷山大,CHENG, XIPING,程西平,XIN,

摘要：: The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the HSD17B13 gene, as well as methods of inhibiting epression of HSD17B13, and methods of treating subjects that would benefit from reduction in expression of HSD17B13, such as subjects having a HSD17B13-associated disease, disorder, or condition, using such dsRNA compositions.本發明係關於靶定HSD17B13基因之雙股核糖核酸(dsRNA)組成物，以及抑制HSD17B13表現之方法，以及使用該dsRNA組成物治療將從HSD17B13表現降低受益之個體的方法，該個體如患有HSD17B13相關疾病、病變或病症者。