CHIMERIC POLYPEPTIDE ASSEMBLY AND METHODS OF MAKING AND USING THE SAME

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专利权人:

发明人:

SCHELLENBERGER VOLKER,YANG FAN,THAYER DESIREE,SIM BEE CHENG,WANG CHIA WEI

申请号：

IN201817004134

公开号：

IN201817004134A

申请日:

2018.02.03

申请国别(地区):

IN

年份:

2018

代理人:

摘要：

The present invention relates to bispecific chimeric polypeptide assembly compositions comprising bulking moieties linked to binding domains by cleavable release segments that, when cleaved are capable of concurrently binding effector T cells with targeted tumor or cancer cells and effecting cytolysis of the tumor cells or cancer cells. The invention also provides compositions and methods of making and using the cleavable chimeric polypeptide assembly compositions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/