Jonathan Albert Back;Samuel Hou;Stanislas Blein;Antoine Attinger;Rami Lissilaa
发明人:
Antoine Attinger,Stanislas Blein,Jonathan Albert Back,Rami Lissilaa,Samuel Hou
申请号：
US13545708
公开号：
US08748585B2
申请日:
2012.07.10
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to antagonist antibodies or fragments thereof that bind to human OX40. More specifically, the present invention relates to an antagonist antibody or fragment thereof that binds to human OX40 comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 1, and/or a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 2, and/or a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO: 3； and/or comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO: 4, and/or a light chain CDR2 comprising the amino acid sequence of SEQ ID NO: 5 and/or a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 6.
