Martha E. Rodriguez;Michael O'Sullivan;David A. Mareska;Jeremy J. Hans;Robert D. Groneberg;Darren M. Harvey
发明人:
Martha E. Rodriguez,David A. Mareska,Jeremy J. Hans,Darren M. Harvey,Robert D. Groneberg,Michael O'Sullivan,Michael OSullivan
申请号：
US13143998
公开号：
US08809538B2
申请日:
2010.01.07
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A method for preventing and/or treating a metabolic disease, cerebrovascular disease, etc. which comprises administering to a mammal an effective amount of the compound of the formula (I):wherein all symbols have the same meanings as defined in the specification； a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof. And a novel compound of the formula (I-1):wherein all symbols have the same meanings as defined in the specification； a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof has an anti-diabetic effect and a neuroprotective effect. Accordingly, the compound of the formula (I) and the compound of the formula (I-1) are useful in a method for preventing and/or treating for a metabolic disease such as diabetes, cerebrovascular disease such as stroke, etc.
