The present invention relates to processes of preparing N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1H-pyrazole-3-sulfonamide and salts thereof. The present invention further relates to pharmaceutical compositions comprising such compounds and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.本發明係關於製備N-((1,2,3,5,6,7-六氫-s-二環戊二烯并苯-4-基)胺甲醯基)-1-異丙基-1H-吡唑-3-磺醯胺及其鹽之方法。本發明進一步係關於包含此類化合物之醫藥組合物及此類化合物最尤其藉由NLRP3抑制來治療及預防醫學病症及疾病之用途。
