MUELLER, JOHN C., JR.,KEENAN, DESMOND BARRY,WANG, LU,MASTROTOTARO, JOHN J.
申请号:
CA2702428
公开号:
CA2702428C
申请日:
2008.10.28
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
A method of calibrating glucose monitor data includes collecting the glucosemonitor data over a period of timeat predetermined intervals, obtaining reference glucose values from areference source that temporally correspond with the glucosemonitor data obtained at the predetermined intervals, calculating thecalibration characteristics using the reference glucose valuesand corresponding glucose monitor data to regress the obtained glucose monitordata, and calibrating the obtained glucose monitordata using the calibration characteristics. In additional embodiments,calculation of the calibration characteristics includes linearregression and, in particular embodiments, least squares linear regression.Alternatively, calculation of the calibration characteristicsincludes non-linear regression. Data integrity may be verified and the datamay be filtered. Further, calibration techniques may bemodified during a fast rate of change in the patient's blood glucose level toincrease sensor accuracy.