BICYCLOHETEROARYL COMPOUNDS AS P2X7MODULATORS AND USES THEREOF农业专利-农业学术服务平台

发明人:: KELLY, MICHAEL G.,麦克G. 凯利,麥克G. 凱利,KINCAID, JOHN,约翰金凯德,約翰金凱德,FANG, YUNFENG,房云峰,房云峰,CAO, YEYU,曹冶宇,曹冶宇,KAUB, CARL,卡尔寇柏,卡爾寇柏,GOWLUGARI, SUMITHRA,沙米斯拉考卢盖里,沙米斯拉考盧蓋里,WANG, ZHAN,王湛,王湛

摘要：: Bicycloheteroaryl compounds are disclosed that have a formula represented by the following:The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.本發明揭露雙環雜芳基化合物,其具有下列所示化學式:該化合物可製備醫藥組合物,並且可用於預防及治療多種哺乳動物,包含人類之症狀,其(以非限制性實施例的方式)包含、疼痛、發炎、創傷性損傷與其他。