MEK inhibits Elixirs System Prepare and inhibits Elixirs System Elixirs comprising MEK农业专利-农业专业知识服务系统

发明人:: C.M.克雷尔,C.M.克雷爾,M.米森,D.A.尼德尔,D.A.尼德爾,W.H.帕钦格,W.H.帕欽格,Mc.沃尔夫,Mc.沃爾夫,D.齐默尔曼,D.齊默爾曼,W.刘,W.劉,P.J.斯滕格尔,P.J.斯滕格爾,P.尼科尔斯,P.尼科爾斯

摘要：: The bright method for being related to Yong Yu System Prepare 6- (the bromo- 2- Fluorophenylamino of 4-) the fluoro- 3- methyl -3H- benzimidazole -5- formic acid of -7- (2- Hydroxyalkyl base oxethyl)-amide of this Hair, Yong Yu System Prepare Knot crystalline substance 6- (the bromo- 2- Fluorophenylamino of 4-) the fluoro- 3- methyl -3H- benzimidazole -5- formic acid of -7- (2- Hydroxyalkyl base oxethyl)-amide method Yi Ji Fitness what the method Zhong Inter Body. This paper It provides the Drug object Group comprising this Knot crystalline substance compound and closes object.本發明涉及用於製備6‑(4‑溴‑2‑氟苯基氨基)‑7‑氟‑3‑甲基‑3H‑苯并咪唑‑5‑甲酸(2‑羥基乙氧基)‑酰胺的方法、用於製備結晶6‑(4‑溴‑2‑氟苯基氨基)‑7‑氟‑3‑甲基‑3H‑苯并咪唑‑5‑甲酸(2‑羥基乙氧基)‑酰胺的方法以及適用於所述方法的中間體。本文還提供包含此結晶化合物的藥物組合物。