The present invention relates to synthetic processes useful in the preparation of compounds of Formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease and have application in the treatment of conditions caused by HCV. In particular, the present invention relates to novel oxidation processes useful for preparing compounds of Formula (I) and related compounds, including pharmaceutically acceptable salts, hydrates and solvates thereof, and including stereoisomers thereof.본원에서는, 하기 구조 화학식 I의 화합물의 고체 무정형 형태를 포함하며 BET 비표면적이 약 94 m2/g 이하인 약물 물질, 상기 약물 물질을 포함하는 제약 조성물, 상기 약물 물질의 제조 방법, 및 상기 약물 물질 및 제약 조성물의 용도를 개시한다.<화학식 I>
