Способ сравнительной интегральной оценки на популяционном уровне формирования тиреоидных нарушений у населения в условиях воздействия различных факторов производственного процесса и/или среды обитания
Federalnoe byudzhetnoe uchrezhdenie nauki "Federalnyj nauchnyj tsentr mediko-profilakticheskikh tekhnologij upravleniya riskami zdorovyu naseleniya" Federalnoj sluzhby po nadzoru v sfere zashchity pra
发明人:
Zajtseva Nina Vladimirovna,Зайцева Нина Владимировна,Luzhetskij Konstantin Petrovich,Лужецкий Константин Петрович,Chigvintsev Vladimir Mikhajlovich,Чигвинцев Владимир Михайлович,Ustinova Olga Yurevna
申请号：
RU2016142976
公开号：
RU0002626585C1
申请日:
2016.10.31
申请国别(地区):
RU
年份:
2017
代理人:
摘要：
FIELD: medicine.SUBSTANCE: population groups to be compared are selected. The values of the following laboratory marker indicators of thyroid disorders are determined in each examined person from both groups: free thyroxine (T4) thyroid-stimulating hormone (TSH) antibodies to thyroglobulin (AB to TG) antibodies to thyroid peroxidase (antibodies to TPO). Also, the marker indicators of thyroid gland (TG) ultrasound are determined for the presence or absence of an increase in its volume above/below the physiological norm, a violation of its structure and/or blood flow. For each group, an average value is determined for each marker. For quality indicators, average values are found, taking the "zero" value in the absence of deviations from normal, and the "one" value in the event of deviations from the specified norm. Using the indicated average values for each marker, the contribution of each of them to thyroid disorders formation is determined. To do this, the parabolic law is used to determine the deflection function Fi, where Fi∈[01], for each 1st marker. Each average marker diagnostic index is given an expert weighting factor Ci. The value of the integral index P is computed for the aggregate of these marker indicators for each population group to be compared, according to the claimed formula. Then, the established integral indices are compared for each group, and those that are characterized by a larger value of the integral index are considered to be a group with a higher risk of thyroid disorders formation at the population level.EFFECT: method allows to conduct an informative and demonstrative comparative integral evaluation of thyroid disorders formation at the population level, to judge the differences in the conditions of impact of various negative factors due to a comprehensive evaluation of the most significant indices.3 cl, 3 tblИзобретение относится к медицине и экологии. Производят выборку групп населения, подлежащих сравнению. Определяют у каждого обсле
