PROBLEM TO BE SOLVED: To provide medicaments for treating, reducing or preventing functional dyspepsia, e.g. the intensity of stomach fullness, nausea, bloating after the ingestion of small or larger meals, especially of fat containing or fat rich meals.SOLUTION: The invention relates to the medicaments characterized by comprising an effective amount of the lipase inhibitor, preferably, orlistat. The invention relates to the internal medicine for treating, reducing or preventing functional dyspepsia. According to the present invention, inhibition of fat digestion by orlistat reduces the intensity of postprandial dyspeptic symptoms.COPYRIGHT: (C)2008,JPO&INPIT【課題】機能性消化不良、例えば、少量または多量の食事、特に、脂肪を含むまたは脂肪を多く含む食事を摂取した後の胃膨満強度、悪心、鼓張を治療、軽減または予防する医薬の提供。【解決手段】有効量のリパーゼ阻害物質、好ましくはオルリスタットを含有することを特徴とする医薬。さらに好ましくは機能性消化不良を治療または予防するための内用薬。オルリスタットによる脂肪の消化の阻害は、食後の消化不良症状の強さを低下させる。【選択図】なし