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COMPLEXES D'ACIDES AMINES MINERAUX D'AGENTS ACTIFS
专利权人:
THETIS PHARMACEUTICALS LLC
发明人:
SCIAVOLINO, FRANK C.,MATHIAS, GARY
申请号:
CA2951923
公开号:
CA2951923A1
申请日:
2015.06.12
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention provides compounds of Formula I and related compositions and methods. Formula (I). R1 and R2each refer to a branched or unbranched carbon chain of from 1 to 20 carbons having at least one basic function; R1 and R2 are the same or different; X1 and X2 are independently selected from H and -CO-Z, where Z is a peptide moiety incorporating from 1 to 5 amino acids, or a pharmaceutically acceptable salt thereof; X1 and X2 are the same or different; M is a divalent metal cation selected from magnesium (Mg2 +), calcium (Ca2+), and zinc (Zn2+); A and B are each a molecule having at least one acidic function, either A or B, but not both, may be absent, and when both A and B are present, A and B may be the same or different. In a particular embodiment, at least one of "A" and "B" or both are fatty acids. A representative example of the application is the compound Magnesium Lysinate bis docosapentaenoic acid shown hereafter, Formula; The complexes of the application are intended for pharmaceutical compositions or as food additive, notably to treat conditions responsive to treatment with polyunsaturated fatty acids.
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