James L. Ratcliff;David R. Drake;Sally A. Cunningham;Elena J. Young
发明人:
James L. Ratcliff,David R. Drake,Sally A. Cunningham,Elena J. Young
申请号:
US12731271
公开号:
US08926951B2
申请日:
2010.03.25
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A composition and method of stabilized chlorine dioxide at a concentration range of about 0.005% to about 0.800% (w/v) at a pH in the range of 6.0 to 7.4 for the prevention of oral diseases caused by dental biofilm and plaque accumulation, such as gingivitis and periodontitis, through bactericidal properties is disclosed. The bactericidal properties of stabilized chlorine dioxide are further expanded to include reduction (kill) of anaerobic/aerobic/facultative gram-negative and gram-positive oral bacteria occurring in plaque or polymicrobial biofilms. The composition may be in the form of wash, rinse, soak, paste, gel, aerosol spray, or other suitable delivery system.