Stewart Russell,Edward A. Fisher,Youssef Zaim Wadghiri,Ryan Casey
申请号:
US15821647
公开号:
US20190271677A1
申请日:
2017.11.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention provides methods and kits for detecting the presence of, the amount of, or the concentration of a substantially non-emitting metal in a sample by a) providing a sensitizer to a chelator of the substantially non-emitting metal thereby creating a sensitized-metal complex; b) adding an unsensitized chelate, and c) detecting a signal from the unsensitized chelate. The substantially non-emitting metal may be gadoliniumn and may exist in complex with a chelator. The unsensitized chelate may be terbium (Tb) or europium (Eu) and the detecting a signal may be performed by fluorescence.