COMPOSITIONS DE CHELATION DE METAL POLYMERE ET LEURS PROCEDES DE PREPARATION POUR REGULER LA CROISSANCE ET LES ACTIVITES DE CELLULES ET D'ORGANISMES VIVANTS
HOLBEIN, BRUCE E.,ANG, M. TRISHA C.,PALASKAR, DNYANESHWAR VITHOBA,SATYANARAYANA, GANUGAPATI,MAHANDRU, GIREESH,REDDY, S. VIJAYA BHASKARA,ALI, SAZID
申请号：
CA3034540
公开号：
CA3034540A1
申请日:
2017.08.25
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Disclosed are chelating co-polymer compositions that are soluble in aqueous media and chelate essential metals, methods of preparation and uses thereof. The chelating compositions are comprised of two or more different monomers, at least one of which possesses metal binding or metal chelating activity. The chelating compositions are synthesized by reversible addition-fragmentation transfer (RAFT) polymerization with the aid of a suitable RAFT-mediating agent. Also described are chelating compositions that comprise hydroxypyridinone chelating groups. The ability of the chelating compositions to bind metals affects the activity of a living cells and organisms, which require the metals for cellular functions.
