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Polysialic acid and use for treatment of neurodegenerative and neuroinflammatory diseases
专利权人:
RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT BONN;UNIVERSITÄT ZU KÖLN
发明人:
Harald Neumann,Jens Kopatz,Anahita Shahraz,Marcus Karlstetter,Thomas Langmann
申请号:
US14779800
公开号:
US09944721B2
申请日:
2014.03.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a branched or unbranched free or glycosidically bound polysialic acid according to general formula (1) as given as follows poly-(α(2→8 or 2→9)Neu5Ac)n (1) wherein Neu5Ac is N-acetylneuraminic acid, and n is an integer in the range from 14 to 26 and/or pharmaceutically acceptable salts thereof, a polysaccharide composition comprising the polysialic acid (1), and the use as a medicament, particularly in the therapeutic and/or prophylactic treatment of degenerative, demyelinating and inflammatory diseases of the central nervous system, and degenerative or inflammatory retinal diseases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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