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Administration d'anticorps anti-CD3 dans le traitement de maladies auto-immunes
专利权人:
Tolerrx Inc.
发明人:
申请号:
EP11190677.2
公开号:
EP2433650A3
申请日:
2007.06.05
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
A method of treating an autoimmune disease, such as, diabetes or psoriasis, by administering an anti-CD3 antibody, or anti-CD3 antibody fragment. The anti-CD3 antibody, or anti-CD3 antibody fragment, is administered over a course of treatment wherein, during the course of treatment, the anti-CD3 antibody, or anti-CD3 antibody fragment is administered in a total amount which does not exceed 300 µg/kg when administered intravenously or, when administered other than intravenously, is administered in a total amount that does not exceed a total amount bioequivalent to 300µg/kg of intravenous administration thereof.
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