CHANG, GREGORY P.,CHEUNG, ANN F.,GRINBERG, ASYA,HANEY, WILLIAM,LUNDE, BRADLEY M.,PRINZ, BIANKA
申请号:
CA3090244
公开号:
CA3090244A1
申请日:
2019.02.08
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Antibody heavy chain variable domains that can be paired with antibody light chain variable domains to form an antigen-binding site targeting the NKG2D receptor on natural killer cells are described. Proteins comprising an NKG2D antigen-binding site, pharmaceutical compositions and therapeutic methods thereof, including for the treatment of cancer, are also described.