A composition comprising (-) -trans-3- (5, 6-dihydro-4H-pyrrolo [3,2,1-ij] quinolin-1-yl)-4-(1H-indol-3-yl) pyrrolidine- 2, 5-dione in combination with a second anti-proliferative agent
Kyowa Hakko Kirin Co.;Kyowa Hakko Kirin Co., Ltd.;ArQule, Inc.; Ltd.
发明人:
Chan, Thomas C. K.,France, Dennis S.,Ishii, Kenichi,Pucci, Paolo
申请号：
AU2010213696
公开号：
AU2010213696B2
申请日:
2010.02.11
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or a pyrroloquinolinyl-pyrrolidine-2,5-dione compound in combination with a therapeutically effective amount of a second anti-proliferative agent.
