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4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists
专利权人:
Janssen Pharmaceutica N.V.
发明人:
MacDonald, Gregor James,Bartolome-Nebreda, Jose Manuel
申请号:
AU2008240728
公开号:
AU2008240728B2
申请日:
2008.04.18
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention relates to (1-benzyl-piperidin-4-yl) - (4-alkoxy-pyridazin-3-yl)- amines of formula (I) that are fast dissociating dopamine 2 receptor antagonists,processes for preparing these compounds, pharmaceutical compositions comprisingthese compounds as an active ingredient. The compounds find utility as medicinesfor treating or preventing central nervous system disorders, for example schizophrenia,by exerting an antipsychotic effect without motor side effects.
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