A method for monitoring an amount of a contrast agent within an object 12 is provided. The method includes obtaining contrast data from one or more images 30 of an object 12 via an imaging device 18, 20. The contrast data corresponds to the contrast agent. The method further includes calculating a measured amount of the contrast agent for each of the one or more images 30 by applying a kinetic model 70 to the contrast data, and generating a predictive curve 68 of the amount of the contrast agent via the kinetic model 70. The kinetic model 70 generates the predictive curve 68 based at least in part on the measured amount of the contrast agent for each of the one or more images 30.