application of 18-methyl-15beta, 16beta-methylen-19-nor-20-spirox-4-en-3-ones in menorrhagia therapy, as well as intrauterine systems containing 18-methyl-15beta, 16beta-methylen-19-nor -20-spirox-4-en-3-ones for therapy of uterine bleeding disorders
HARRI JUKARAINEN,HENRIIKKA KOROLAINEN,KATJA PRELLE,LARS RÖSE,NORBERT SCHMEES,REINHARD NUBBEMEYER,TUULA
申请号：
BR112014026086
公开号：
BR112014026086A2
申请日:
2013.04.19
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
Patent Application: "Application of 18-methyl-15beta, 16beta-methylen-19-nor-20-spirox-4-en-3-ones in menorrhagia therapy, as well as intrauterine systems containing 18-methyl-15beta, 16beta" -methylen-19-nor-20-spirox-4-en-3-ones for the therapy of uterine bleeding disorders ". The present invention relates to the description of the intrauterine application of 18-methyl-15β, 16β-methylen-19-nor-20-spirox-4-en-3-one of the general formula (i), (1) wherein r6 and R 7 represent hydrogen or a methylene group in the therapy of menorrhagia, generally of uterine bleeding, as well as an intrauterine system for the above application containing a compound of formula (i).resumo patente de invenção: "aplicação de 18-metil-15beta,16beta-metilen-19-nor-20-spirox-4-en-3-onas na terapia da menorragia, bem como sistemas intrauterinos contendo 18-metil-15beta,16beta-metilen-19-nor-20-spirox-4-en-3-onas para a terapia de distúrbios de sangramento uterino". a presente invenção refere-se a descrição da aplicação intrauterina de 18-metil-15ß,16ß-metilen-19-nor-20-spirox-4-en-3-ona da fórmula geral (i), (1) na qual r6 e r7 representam hidrogênio ou um grupo metileno, na terapia da menorragia, de modo geral de sangramentos uterinos, bem como um sistema intrauterino para a aplicação mencionada contendo um composto da fórmula (i).
