Robert Mattrey,Zhe Wu,Emilia Olson,Joseph Wang,Wei Gao,Christopher D. Malone
申请号:
US14407450
公开号:
US09713459B2
申请日:
2013.06.11
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A method and system are provided for detection of localized hydrogen peroxide within tissue by introducing a catalase-containing material into at location of interest, positioning an ultrasound transducer over the location, and generating an ultrasound image to detect microbubbles, where the presence of microbubbles indicate the presence of localized hydrogen peroxide. The catalase-coated surface may be the inner surface of a microtube, on the surface of or incorporated within a nanosphere or microsphere, or an implantable device.