KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION;SNU RDB FOUNDATION
发明人:
CHO, NAM-HYUK,CHEONG, TAEK-CHIN,SEONG, SEUNG-YONG,MIN, JI HYUN,WU, JUN HUA,KIM, YOUNG-KEUN
申请号:
EP10828515
公开号:
EP2500350A4
申请日:
2010.11.03
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention relates to a complex of a protein comprising zinc oxide-binding peptides and zinc oxide nanoparticles, to the use thereof as a drug delivery carrier for manufacturing medicines, and to a vaccine composition and a contrast agent comprising the composite. The protein comprising zinc oxide-binding peptides significantly improves the in vivo availability of zinc oxide-binding peptides, and therefore the complex of the present invention can be used not only as a drug delivery carrier for in vivo drug delivery or intracellular drug delivery, but also for in vivo imaging or cell imaging. The complex can be used for producing separating agents for effectively separating biological materials, therapeutic agents for hyperthermia, etc., contrast agents for MRI, and beads applicable to biosensors.