Particle size reduction of an antimuscarinic compound

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专利权人:

CHIESI FARMACEUTICI S.p.A.

发明人:

Irene Pasquali,Andrea Casazza,Elena Losi,Mark Saunders

申请号：

US14258147

公开号：

US09393202B2

申请日:

2014.04.22

申请国别(地区):

US

年份:

2016

代理人:

摘要：

A stable crystalline micronized particulate of a glycopyrronium salt may be prepared by suspending the drug in a water-immiscible anti-solvent in which the drug has little or no solubility and micronizing the suspension. The resulting drug particles are physically stable with regard to agglomeration and/or aggregation on storage.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/