The antibody provided by the invention is connected to Ly75. Nucleic acid molecules are also provided for encoding antibodies, expression vectors, host cells, and antibody expression programs. Antibodies can be used to treat cancer, including pancreatic cancer, ovarian cancer, breast cancer, rectal cancer, Isogo cancer, skin cancer, thyroid cancer, lung cancer, bladder cancer, multiple spinal cord cancer and lymphoma.La invencion proporciona anticuerpos que se unen a LY75. Tambien se proporcionan moleculas de acido nucleico que codifican los anticuerpos, vectores de expresion, celulas hospedadoras y procedimientos para expresar los anticuerpos. Los anticuerpos se pueden usar para el tratamiento del cancer, incluyendo cancer de pancreas, cancer de ovario, cancer de mama, cancer colorrectal, cancer de esofago, cancer de piel, cancer de tiroides, cancer de pulmon, cancer de vejiga, mieloma multiple y linfoma