KERBAGE, CHARLES,VLOCK, DANIEL R.,MYERS, JOYCE,NILAN, DENNIS J.
申请号:
CA3031528
公开号:
CA3031528A1
申请日:
2017.07.31
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
A system and method for detecting in an eye, in particular the retina, of a mammal, tau protein, such as neurofibrillary tangles (NFT). The system and method can use fluorescence imaging in the visible or near-infrared spectral region, for example as a non-invasive method for in vivo imaging of tau protein in ocular tissue. In preferred embodiments, in vivo imaging of tau protein in ocular tissue involves tau-binding compounds such as FDDNP, T807 and T808.