Jenny Louie-Helm;Gloria Gusler;Bret Berner;John N. Shell
发明人:
Bret Berner,Jenny Louie-Helm,Gloria Gusler,John N. Shell
申请号：
US13156225
公开号：
US08329215B2
申请日:
2011.06.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by permitting diffusion of the drug from the core. The shell also motes gastric retention of the dosage form by swelling upon imbibition of gastric fluid to size that is retained in the stomach during the postprandial or fed mode.
