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USE OF DRONEDARONE ALONE OR IN COMBINATION FOR PREPARING A MEDICAMENT FOR THE TREATMENT OF PATIENTS WITH ARRHYTHMIA AND HAVING AN INCREASE OF CREATININE LEVEL
专利权人:
SANOFI-AVENTIS
发明人:
CLAUDEL, SOPHIE,GAUDIN, CHRISTOPHE
申请号:
NZ58888609
公开号:
NZ588886A
申请日:
2009.04.28
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
Disclosed is the use of dronedarone or one of its pharmaceutically acceptable salts for preparing a medicament for the treatment of arrhythmia, wherein the arrhythmia is in a patient having an increase of creatinine level due to dronedarone administration, said creatinine level increasing following dronedarone treatment initiation, said creatinine level increase reaching a plateau and being used as a new baseline, said creatinine level increase being reversible after dronedarone discontinuation, wherein said medicament is in a form for administration according to a treatment regime which involves the following steps: initiating dronedarone treatment; measuring serum creatinine level increases following dronedarone treatment initiation, which provides a reference level, said serum creatinine level reaching a plateau; discontinuing temporarily dronedarone; measuring that the increase is reversible after dronedarone discontinuation; and continuing dronedarone treatment.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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