The present invention provides (S)-N-(2-(4-chlorophenyl)-2-morpholinoethyl)-2- (pyrimidin-2-yl)-4-(trifluoromethyl)thiazole-5-carboxamide as P2X7 inhibitor, its use as a medicament, and a convenient enantiomeric synthesis protocol for the preparation of (S)- N-(2-(4-chlorophenyl)-2-morpholinoethyl)-2-(pyrimidin-2-yl)-4-( trifluoromethyl)thiazole-5-carboxamide.La presente invención proporciona (S)-N-(2-(4-clorofenil)-2-morfol inoetil)-2-(pirimidin-2-il)-4-(trifluorometil)tiazol-5-carboxamid a como inhibidor de P2X7, su uso como medicamento y un protocolo de síntesis enantiomérica conveniente para la preparación de (S)-N-(2-(4-clorofenil)-2-morfolinoetil)-2-(pirimidin-2-il)-4-(tr ifluorometil)tiazol-5-carboxamida.